SWITNAP-D 500

Composition (Each tablet contains):

• Naproxen Sodium USP – 500 mg

• Domperidone Maleate I.P. (eq. to Domperidone) – 10 mg

🩺 Product Description:

SWITNAP-D 500 is a combination of a non-steroidal anti-inflammatory drug (NSAID) – Naproxen Sodium and a prokinetic agent – Domperidone, used primarily in the treatment of migraine headaches, musculoskeletal pain, and gastric discomfort associated with NSAID therapy. This dual-action formulation relieves pain and inflammation while also managing nausea and gastric side effects.

💊 Uses:

• Treatment of acute migraine attacks

• Relief of headache with nausea or vomiting

• Menstrual pain (dysmenorrhea)

• Musculoskeletal pain (back pain, sprains, arthritis)

• Pain and inflammation with accompanying gastric discomfort

• Fever with nausea

💡 Benefits:

• Naproxen Sodium is a powerful NSAID that reduces inflammation, pain, and fever by inhibiting prostaglandin synthesis.

• Domperidone prevents nausea, bloating, and vomiting commonly associated with migraine or NSAID intake.

• Provides faster relief in migraines by addressing both headache and nausea simultaneously.

• Reduces gastric side effects of NSAIDs by enhancing gastric motility.

• Enhances patient compliance in conditions involving both pain and digestive upset.

🧭 Indications:

• Migraine with or without aura

• Tension headache with nausea

• Postoperative pain with gastric distress

• Gastro-intestinal discomfort due to NSAIDs

• Fever and flu-like symptoms with gastric issues

📌 Dosage:

• Adults: One tablet twice daily after meals or as prescribed by the physician.

• Do not crush or chew.

• Maximum daily dose of Naproxen: 1000 mg (unless otherwise prescribed).

• Duration: Short-term use recommended unless advised for extended therapy.

⚠️ Side Effects:

Common side effects may include:

• Gastric irritation or heartburn

• Dry mouth

• Headache or dizziness

• Constipation or diarrhea

• Drowsiness or fatigue

• Rare: Allergic rash, increased liver enzymes

Seek medical attention if severe allergic reactions, black/tarry stools, or persistent abdominal pain occurs.

🔄 Drug Interactions:

• Antacids & H2 blockers: May reduce Domperidone’s efficacy.

• Anticoagulants (e.g., Warfarin): Increased risk of bleeding with Naproxen.

• Antifungals (Ketoconazole, Fluconazole): May increase Domperidone levels.

• SSRIs, corticosteroids, lithium – Use with caution.

Always consult a physician before combining medications.

🚫 Precautions & Warnings:

• Avoid in patients with peptic ulcers, severe hepatic or renal impairment.

• Not recommended in pregnancy or lactation unless prescribed.

• Use cautiously in elderly patients or those with cardiac conditions.

• Not for children under 12 years.

• Avoid alcohol; it may worsen gastric irritation.